abstract：:In a retrospective analysis, 63 participants in a cardiac rehabilitation-preventive cardiology program were identified as having low blood concentrations (mean, 34 mg/dl) of high-density lipoprotein cholesterol (HDL-C) and a mean total cholesterol level of 223 mg/dl after 3 months of hygienic measures (aerobic exercis...

journal_title：Mayo Clinic proceedings

authors： Squires RW,Allison TG,Gau GT,Miller TD,Kottke BA

更新日期：1992-09-01 00:00:00

abstract：:In this study, our aim was to test the hypothesis that colonic tone is abnormal in patients with irritable bowel syndrome (IBS). We studied eight patients with IBS and eight age-matched asymptomatic control subjects, in whom tone and motility were measured by an electronic barostat and by pneumohydraulic perfusion man...

journal_title：Mayo Clinic proceedings

authors： Vassallo MJ,Camilleri M,Phillips SF,Steadman CJ,Talley NJ,Hanson RB,Haddad AC

更新日期：1992-08-01 00:00:00

abstract：:By identifying structural chromosome anomalies, the clinical cytogenetics laboratory can play a critical role in the diagnosis and treatment of patients with birth defects. Although many new staining techniques have been developed throughout the years to aid in the detection of anomalous chromosomes, some abnormalitie...

journal_title：Mayo Clinic proceedings

authors： Kraker WJ,Borell TJ,Schad CR,Pennington MJ,Karnes PS,Dewald GW,Jenkins RB

更新日期：1992-07-01 00:00:00

abstract：:To determine factors associated with a favorable long-term prognosis in gastric leiomyosarcoma, we retrospectively reviewed the medical records of 93 Mayo Clinic patients with this biopsy-proven tumor diagnosed during the 25-year period from 1964 through 1988. Six patients who had Carney's triad (gastric epithelioid l...

journal_title：Mayo Clinic proceedings

authors： Farrugia G,Kim CH,Grant CS,Zinsmeister AR

更新日期：1992-06-01 00:00:00

abstract：:As part of a multicenter investigative trial, transurethral microwave thermotherapy of the prostate was used in 60 men with symptomatic benign prostatic hypertrophy. A single office treatment on the Prostatron, a device that provides concurrent microwave heating of the prostate and conductive cooling of the urethra, w...

journal_title：Mayo Clinic proceedings

authors： Blute ML,Tomera KM,Hellerstein DK,Atkinson EJ,Patterson DE,Segura JW

更新日期：1992-05-01 00:00:00

abstract：:Prospective data and follow-up information were collected on the initial 200 patients who underwent laparoscopic cholecystectomy at the Mayo Clinic. The operation was completed laparoscopically in all but five patients, who required conversion to laparotomy because of dense scarring or stones in the common bile duct. ...

journal_title：Mayo Clinic proceedings

authors： Donohue JH,Farnell MB,Grant CS,van Heerden JA,Wahlstrom HE,Sarr MG,Weaver AL,Ilstrup DM

更新日期：1992-05-01 00:00:00

abstract：:The source of the membranous materials that accumulate in distal axons of rats intoxicated with p-bromophenylacetylurea (BPAU) was studied by electron microscopy. 35S-Methionine was injected into the ventral horn of the spinal cord at 2, 14, and 35 days after injection of BPAU. Three days later, samples of the deep pe...

journal_title：Mayo Clinic proceedings

authors： Oka N,Brimijoin WS

更新日期：1992-04-01 00:00:00

abstract：:B-cell chronic lymphocytic leukemia (B-CLL) is a relatively indolent hematologic malignant disease that, despite a good response to nonaggressive orally administered chemotherapy, currently remains incurable. The overall median duration of survival is more than 5 years, and the presence of anemia or thrombocytopenia a...

journal_title：Mayo Clinic proceedings

authors： Tefferi A,Phyliky RL

更新日期：1992-04-01 00:00:00

abstract：:A 37-year-old man was referred to our institution for assessment of possible sarcoidosis with involvement of the central nervous system. Before referral, he experienced a systemic illness that persisted for several months, during which time ocular and pulmonary noncaseating granulomas were identified. Sarcoidosis with...

journal_title：Mayo Clinic proceedings

authors： Edmonds LC,Stubbs SE,Ryu JH

更新日期：1992-01-01 00:00:00

abstract：:We describe a woman in whom hypogammaglobulinemia and severe granulomatous cutaneous lesions had developed during childhood; subsequently, Hodgkin's disease and necrobiotic xanthogranuloma were diagnosed. This case illustrates an apparent association with disease activity and raises the question of a direct relationsh...

journal_title：Mayo Clinic proceedings

authors： Reeder CB,Connolly SM,Winkelmann RK

更新日期：1991-12-01 00:00:00

abstract：:Type I anti-neuronal nuclear autoantibodies (ANNA-I, also known as "Hu") are a distinctive serologic marker of small cell lung carcinoma (SCLC) in patients who have peripheral neuropathies or encephalomyeloradiculopathies. A tumor antigen reactive with these antibodies has been identified by other investigators by Wes...

journal_title：Mayo Clinic proceedings

authors： Kiers L,Altermatt HJ,Lennon VA

更新日期：1991-12-01 00:00:00

abstract：:Although transthoracic two-dimensional echocardiography has been a procedure of choice for diagnosing cardiac mass lesions, the advent of transesophageal echocardiography (TEE) provided better visualization of cardiac structures, especially those at a considerable depth from the chest wall, and lesions that involve th...

journal_title：Mayo Clinic proceedings

authors： Reeder GS,Khandheria BK,Seward JB,Tajik AJ

更新日期：1991-11-01 00:00:00

abstract：:Vancomycin is a glycopeptide antibiotic that is active against staphylococci, streptococci, and other gram-positive bacteria. It is the drug of choice for the treatment of infections due to methicillin-resistant staphylococci, Corynebacterium jeikeium, and multiply resistant strains of Streptococcus pneumoniae. Vancom...

journal_title：Mayo Clinic proceedings

authors： Wilhelm MP

更新日期：1991-11-01 00:00:00

abstract：:Cephalosporins are broad-spectrum antimicrobial agents that are often used empirically to treat suspected bacterial infections and also to treat culture-proven infections due to selected gram-positive and gram-negative microorganisms. Cephalosporins differ widely in their spectrum of activity, susceptibility to beta-l...

journal_title：Mayo Clinic proceedings

authors： Gustaferro CA,Steckelberg JM

更新日期：1991-10-01 00:00:00

abstract：:To identify the wishes of patients with amyotrophic lateral sclerosis (ALS) for information, participation in decision making, and life-sustaining therapy and to determine whether these wishes are stable over time, we conducted a prospective survey (baseline and 6-month follow-up interviews) of 38 consecutive patients...

journal_title：Mayo Clinic proceedings

authors： Silverstein MD,Stocking CB,Antel JP,Beckwith J,Roos RP,Siegler M

更新日期：1991-09-01 00:00:00

abstract：:Of the 355 patients with tuberous sclerosis complex (TSC) examined at the Mayo Clinic, 49 had died (9 of causes other than TSC). We attempted to determine what pattern of organ involvement occurred most often in the 40 patients who died of TSC. One baby died of cardiac failure due to cardiac rhabdomyomas, and one chil...

journal_title：Mayo Clinic proceedings

authors： Shepherd CW,Gomez MR,Lie JT,Crowson CS

更新日期：1991-08-01 00:00:00

abstract：:Endoscopic esophageal variceal sclerotherapy (EVS) is often used in the treatment of upper gastrointestinal hemorrhage due to esophageal varices. We retrospectively reviewed the Mayo Clinic experience with EVS between 1980 and 1989 to determine the incidence of thoracic manifestations and chest roentgenographic abnorm...

journal_title：Mayo Clinic proceedings

authors： Zeller FA,Cannan CR,Prakash UB

更新日期：1991-07-01 00:00:00

abstract：:Tinnitus, a common complaint, reportedly affects more than 37 million Americans. Most often, it is associated with a sensorineural hearing loss in the high-frequency range. Tinnitus, however, is a symptom and not a disease. Complacency about this symptom complex may cause physicians to overlook a severe underlying pat...

journal_title：Mayo Clinic proceedings

authors： Marion MS,Cevette MJ

更新日期：1991-06-01 00:00:00

abstract：:A follow-up study of 224 male patients from Rochester, Minnesota, diagnosed with cryptorchidism during the period from 1935 through 1974 was conducted to assess the frequency of subsequent testicular neoplasms. Age-specific rates for testicular neoplasm in this community were used to estimate an expected number for co...

journal_title：Mayo Clinic proceedings

authors： Benson RC Jr,Beard CM,Kelalis PP,Kurland LT

更新日期：1991-04-01 00:00:00

abstract：:We reviewed the results of preoperative screening laboratory tests in asymptomatic healthy patients who underwent elective surgical procedures at our institution in 1988. Substantially abnormal results were found in 160 of 3,782 patients. All such abnormalities involved five tests: aspartate aminotransferase, glucose,...

journal_title：Mayo Clinic proceedings

authors： Narr BJ,Hansen TR,Warner MA

更新日期：1991-02-01 00:00:00

abstract：:The sport of snow skiing by the physically disabled, which originated in Europe in 1935 and first received attention in the United States in the 1940s, is reviewed in terms of opportunities available, instructions, adaptive equipment necessary, and benefits provided. Persons with a wide variety of disabilities (such a...

journal_title：Mayo Clinic proceedings

authors： Laskowski ER

更新日期：1991-02-01 00:00:00

abstract：:Amyotrophic lateral sclerosis is an insidiously developing, adult-onset, progressive anterior horn cell degeneration with associated degeneration of descending motor pathways. It has been recognized as an important clinical syndrome since the middle of the 19th century. Despite increasing clinical and research interes...

journal_title：Mayo Clinic proceedings

authors： Williams DB,Windebank AJ

更新日期：1991-01-01 00:00:00

abstract：:Endorectal ultrasonography is a valuable imaging method for examination of the rectum and perirectal tissues. We assessed 50 patients with known rectal carcinoma prospectively by using a 7.0-MHz endorectal transducer to determine the depth of invasion of the rectal wall by tumor and the presence of lymphadenopathy. Tu...

journal_title：Mayo Clinic proceedings

authors： Jochem RJ,Reading CC,Dozois RR,Carpenter HA,Wolff BG,Charboneau JW

更新日期：1990-12-01 00:00:00

abstract：:We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as radioligand, and prior extraction of the native peptide from plasma with C-2 cartridges. We determine...

journal_title：Mayo Clinic proceedings

authors： Kao PC,Klee GG,Taylor RL,Heath H 3rd

更新日期：1990-11-01 00:00:00

abstract：:A need exists for a self-report questionnaire that reliably and accurately measures symptoms and that distinguishes patients with functional gastrointestinal disease from those with other conditions. We have developed such an instrument, the bowel disease questionnaire, and herein describe details of its discriminator...

journal_title：Mayo Clinic proceedings

authors： Talley NJ,Phillips SF,Wiltgen CM,Zinsmeister AR,Melton LJ 3rd

更新日期：1990-11-01 00:00:00

abstract：:We conducted a prospective, randomized trial to study the efficacy and tolerance of long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B. Ten patients were randomly assigned to a 6-month interferon regimen, and 10 patients were assigned to a 3-week interferon t...

journal_title：Mayo Clinic proceedings

authors： Rakela J,Wood JR,Czaja AJ,O'Brien PC,Taswell HF,Bowyer BA,Lange SM,Anderson ML,Parent K

更新日期：1990-10-01 00:00:00

abstract：:During the 11-year period 1975 through 1985, 1,063 surgical procedures were performed on 795 Mayo Clinic patients 90 years of age or older. Preoperative conditions, surgical setting, and perioperative morbidity and mortality were analyzed in a comparison of the local residents of Olmsted County, Minnesota (N = 224), w...

journal_title：Mayo Clinic proceedings

authors： Warner MA,Hosking MP,Lobdell CM,Offord KP,Melton LJ 3rd

更新日期：1990-09-01 00:00:00

abstract：:Two entities of special interest in sleep disorders medicine are restless legs syndrome and periodic movements of sleep. Most patients with restless legs syndrome have periodic movements of sleep, but most patients with the nocturnal disorder do not have restless legs when awake. In both conditions, the underlying cau...

journal_title：Mayo Clinic proceedings

authors： Krueger BR

更新日期：1990-07-01 00:00:00

abstract：:A patient simulator has been developed for training, certification, modeling, and demonstrating problems in the management of critical-care patients. The Critical Care & Hemodynamic Monitoring Training System consists of a personal computer, software, and a replica of a human torso designed to enable students to pract...

journal_title：Mayo Clinic proceedings

authors： Saliterman SS

更新日期：1990-07-01 00:00:00

abstract：:Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures...

journal_title：Mayo Clinic proceedings

authors： Lyons MK,Meyer FB

更新日期：1990-05-01 00:00:00

abstract：:In this article, we describe an integrated approach for detection and evaluation of solitary pulmonary nodules. Initial evaluation of the solitary pulmonary nodule includes tomography, fluoroscopy, and comparison with previously obtained roentgenograms. Subsequently, thin-section computed tomography and phantom densit...

journal_title：Mayo Clinic proceedings

authors： Swensen SJ,Jett JR,Payne WS,Viggiano RW,Pairolero PC,Trastek VF

更新日期：1990-02-01 00:00:00

abstract：:In this report, we describe 13 cases of primary neurofibrosarcoma of the skin. The tumor presumably arises from small cutaneous nerves, is locally aggressive, and has a potential for metastasis. Characteristic histopathologic features include proliferating atypical spindle cells with slender wavy and pointed nuclei; h...

journal_title：Mayo Clinic proceedings

authors： Dabski C,Reiman HM Jr,Muller SA

更新日期：1990-02-01 00:00:00

abstract：:To assess the nature and prognosis of severe chronic active hepatitis of unknown cause, we compared 26 patients who had been fully screened for etiologic factors with 112 patients who had autoimmune chronic active hepatitis after similar durations of corticosteroid therapy (17(+)/- 2 versus 23 (+)/- 2 months), and fol...

journal_title：Mayo Clinic proceedings

authors： Czaja AJ,Hay JE,Rakela J

更新日期：1990-01-01 00:00:00

abstract：:Understanding the sequence of events responsible for pressure-related natriuresis and their pathophysiologic alterations may be useful in distinguishing various types of essential hypertension of renal origin. The perturbation of a distal step in the sequence is likely to be reflected in a simple physiologic defect. F...

journal_title：Mayo Clinic proceedings

authors： Romero JC,Bentley MD,Textor SC,Knox FG

更新日期：1989-11-01 00:00:00

abstract：:Computed tomography (CT) of the colon is useful in assessment of patients with colonic disease because the entire bowel wall, extraluminal tissues, and adjacent solid organs can be directly visualized. Patients with advanced stage colorectal carcinoma can be reliably identified with CT. This information can assist in ...

journal_title：Mayo Clinic proceedings

authors： Johnson CD,Stephens DH

更新日期：1989-10-01 00:00:00

abstract：:A careful clinical history and physical examination are the most important components of the preoperative assessment of the cardiac patient who is to undergo a noncardiac surgical procedure. From these factors and the nature of the surgical procedure planned, a reasonable estimate of potential cardiac risk can be form...

journal_title：Mayo Clinic proceedings

authors： Freeman WK,Gibbons RJ,Shub C

更新日期：1989-09-01 00:00:00

abstract：:Because fasting nerve myo-inositol (myo-Ins) is not decreased in patients with diabetes treated conventionally, in whom neuropathy may develop or may have already developed, it seems unlikely that myo-Ins is the metabolic abnormality that initiates diabetic neuropathy, if nerve myo-Ins is not spuriously high during fa...

journal_title：Mayo Clinic proceedings

authors： Dyck PJ,Minnerath SR,O'Brien PC

更新日期：1989-08-01 00:00:00

abstract：:During the past 20 years, the diagnosis and treatment of ectopic pregnancy have improved considerably. With the current diagnostic modalities, patients at risk for ectopic pregnancy can be followed expectantly, and the diagnosis can be made within a few days of the time of anticipated menses. An enhanced understanding...

journal_title：Mayo Clinic proceedings

authors： Ory SJ

更新日期：1989-07-01 00:00:00

abstract：:Neuroepidemiology has been important in providing clues about the cause and pathogenesis of multiple sclerosis. In this review, we update the incidence and prevalence rates of multiple sclerosis in Olmsted County, Minnesota, and examine the potential role of viruses, exposure to animals, toxins, trauma, and diet in th...

journal_title：Mayo Clinic proceedings

authors： Wynn DR,Rodriguez M,O'Fallon WM,Kurland LT

更新日期：1989-07-01 00:00:00

abstract：:Crohn's disease can involve any portion of the digestive tract, but isolated gastric Crohn's disease is a rare entity. In the few previously reported cases, the inflammatory disorder has involved only a portion of the stomach. Herein we describe a patient with diffuse involvement of the entire stomach and an associate...

journal_title：Mayo Clinic proceedings

authors： Cary ER,Tremaine WJ,Banks PM,Nagorney DM

更新日期：1989-07-01 00:00:00